The firm's Hong Kong office said it accepted the payment in relation to work with local companies specializing in cryptocurrencies and blockchain technology.
The transaction was reportedly made using Bitcoin in exchange for advisory services.
PwC Asia-Pacific chairman Raymund Chao said: "It is an indication that Bitcoin and other established cryptocurrencies have now developed into more broadly accepted forms of settlement."
PwC has a history with cryptocurrencies and blockchain technology going back as far as 2014. From early statements on Bitcoin's role in driving innovation in a number of industries, the company has moved into conducting research and offering its own consultancy services around the technology.
“In our view, cryptocurrency represents the beginning of a new phase of technology-driven markets that have the potential to disrupt conventional market strategies, longstanding business practices, and established regulatory perspectives – all to the benefit of consumers and broader macroeconomic efficiency,” PwC explained.